FORMULATION AND EVALUATION OF TRANSDERMAL PATCH USING ANTIOXIDANT PHYTOCONSTITUENT

Deepak Kumar Patel; Bina Gidwani; Anshita Gupta; Jyoti Sahu; Dr. Chanchal Deep Kaur

doi:10.53555/bs.v2i4.1650

Deepak Kumar Patel Shri Rawatpura Sarkar Institute of Pharmacy
Bina Gidwani Shri Rawatpura Sarkar Institute of Pharmacy,
Anshita Gupta Shri Rawatpura Sarkar Institute of Pharmacy
Jyoti Sahu Shri Rawatpura Sarkar Institute of Pharmacy,
Dr. Chanchal Deep Kaur Shri Rawatpura Sarkar Institute of Pharmacy,

DOI: https://doi.org/10.53555/bs.v2i4.1650

Keywords: Curcumin, Poly Vinayl Pyrollidone, Ethyl Cellulose, Transdermal Patch

Abstract

Conventional drug delivery system has many problems so bulk of research has now shifted
from synthetic drugs to herbal drugs. This is possible because of the vast variety of bioactive
molecules in the plants and their higher safety margin. This present study is focused on the
use of curcumin, the active constituent of Curcuma longa (haldi), and belonging to family
Zingiberaceae as an antioxidant agent. The main objective of present work was to develop the
transdermal patch of curcumin using polymer blends so that minimize the side effects and
maximize the therapeutic efficacy. The formulations were also evaluated for weight variation,
moisture uptake, thickness, moisture content, and folding endurance. Shows satisfactory
results.